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The US makes up 4.6% of the world population and consumes 50% of the manufactured drugs; 80% of the global opioids; 99% of the hydrocodone and 67% of the worlds illegal drugs.(Pain Physicians, 2008,11,S63-S88). Oxycondone and combinations increased 403% from 1997-2002. Gilson AM, Ryan KM, Joranson DE, Dahl JL. (J Pain Symptom Manage 2004;28:176-188)

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